Preheat your oven to 450 degrees Fahrenheit.
Cut the cauliflower into large chunks.
Line a rimmed baking sheet with parchment paper (this makes clean-up easier!) Place the cauliflower on the baking sheet and toss it with olive oil, salt, chili powder, garlic powder, or any seasonings of your choice.
Cover tightly with foil and bake for 15 minutes. This will prevent the cauliflower from burning during the roasting process.
Remove the cauliflower from the oven and remove the foil. Place the cauliflower back in the oven, this time uncovered, and continue roasting for 35-40 minutes, or until the cauliflower starts to turn brown.
Remove from the oven, and adjust seasonings according to taste- you may need a little more salt. Enjoy!